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Lyovapor™ L-300

First lab Freeze Dryer for continuous sublimation

With Infinite-Technology™ the Lyovapor™ L-300 offers continuous sublimation for the first time with two alternately working and automatically hygienically cleansed condensers at -105 °C. In addition, Infinite-Control™ allows entire process control of all relevant parameters, also via mobile devices.

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  • Infinite ice capacity due to alternate loading
  • Stable pressure due to Smart-Switch
  • Reproducible process due to stable parameters: cooling temperature, shelf temperature variation ±1 °C and vacuum pressure
  • Lyophilization of water and organic based solvents at -105 °C


  • User-friendly and clearly arranged touch-screen control panel
  • Get push notifications and process parameters anytime, anywhere using the BUCHI Monitor App
  • Advanced software for creating and managing methods, data recording and reporting
  • Maximum flexibility regarding display positioning (at front or side)
  • Save your precious product by sample protection state


  • Less maintenance due to fully automatic and hygienic cleaning of the ice condenser
  • Always ready to use due to infinite capacity
  • Just one device needed for different users
  • Low energy consumption due to small ice condenser volume


Endless control anywhere, anytime of your freeze drying process due to interface, software and App.

Automated Cleaning

An integrated steam generator melts the ice and cleans the condenser hygienically.

End point determination

Temperature difference can be used together with optional product temperature sensors to determine the end point.

Flexible drying chambers

Flexible drying chambers

  • Adjustable shelf distance according to your application needs
  • Possibility to link two manifold racks together
Ergonomic handling

Ergonomic handling

  • Easy reading of process parameters due to the adjustable display
  • Adaptable position of the display at the front or on the side
Second Interface


Upgrade to Interface Pro anytime to enable working within the advanced Lyovapor™ Software.