Lyovapor™ L-300
First lab Freeze Dryer for continuous sublimation
With Infinite-Technology™ the Lyovapor™ L-300 offers continuous sublimation for the first time with two alternately working and automatically hygienically cleansed condensers at -105 °C. In addition, Infinite-Control™ allows entire process control of all relevant parameters, also via mobile devices.
Features
An integrated steam generator melts the ice and cleans the condenser hygienically.
Optimize your process by combining temperature difference with optional product temperature sensors for reliable endpoint determination.
Easily read process parameters thanks to an adjustable display that can be placed at the front or on the side of the freeze dryer.
Adjust the shelf distance to suit your application needs. Link three manifold racks together for more versatility in your freeze-drying process.
The combination of interface, software and a user-friendly app enables you to continuously control and monitor your freeze-drying process from anywhere at any time.
Take advantage of the most advanced features of Lyovapor™ L-300 with the Lyovapor™ Software and a simple upgrade to Interface Pro.
Compare the Lyovapor™ L-300
Lyovapor™ L-300 Continuous with 24 manifold rack
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:-
- Drying shelf temperature tolerance:-
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 36 manifold rack
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:-
- Drying shelf temperature tolerance:-
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 4 non heating shelves, 12 manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:-
- Drying shelf temperature tolerance:-
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 6 non heating shelves, 12 manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:-
- Drying shelf temperature tolerance:-
- User interphase:4.6 in
Lyovapor™ L-300 Pro with 4 heating shelves
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Pro with 4 heating shelves, stoppering cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Pro with 6 heating shelves
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Pro with 6 heating shelves, manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
"The Lyovapor™ L-300 is the highly automated freeze dryer with continuous defrosting and 36 manifold positions providing less instrument downtime. The usage in the laboratory with open access and in small molecule synthesis with high sample throughput are the key features for high productivity."David Wechsler - Medicinal Chemistry, Roche Pharma Research and Early Development, Basel
Related Parts & Accessories
Pirani/piezo pressure sensor, with cable for pressure regulation
Pirani / piezo pressure sensor with reading from 0.03 - 1200 mbar on BUCHI Lyovapor.
Manifold valve with JS 29/32
Manifold valve for fast sample connection. Made of EPDM/Silicone with joint size 29/32.
Adapter for ampoules
Adapter for 19 ampules for direct connection to manifold valve to one of the BUCHI Lyovapors™.
Oil-free vacuum pump
Dry scroll vacuum pump (Edwards nXDS10iC) with high chemical stability and a pumping speed of 10 m3/h at 50 Hz and 60 Hz for the Lyovapor™ L-300.
Set drying bottle 800 mL
Beaker flask with rubber cap for direct connection to manifold valves including filter paper and O-ring.
Drying rack with 12 manifold valves
Using the drying rack with 12 manifold valves and a base plate, connect up to 12 samples to a BUCHI Lyovapor™.
Manifold rack with 24 positions
Connect up to 24 samples to a BUCHI Lyovapor™ with the drying rack with 24 manifold valves and base plate.
Drying chamber with four unheatable shelves
The acrylic glass drying chamber with a top cover and four non-heatable shelves is an accessory for BUCHI Lyovapor™.
Drying chamber with four unheatable shelves, twelve manifolds
An acrylic glass drying chamber with a top cover features 12 manifold valves and 4 non-heatable shelves for BUCHI LyovaporTM.
Drying chamber with six unheatable shelves
The acrylic glass drying chamber has a top cover and six non-heatable shelves for BUCHI Lyovapor™.
Downloads
- Technical Data Sheet Lyovapor L-300(pdf)
- Solution Brochure Freeze Drying en(pdf)
- Product Brochure Pharma and Chemistry en(pdf)
- Operation Manual Lyovapor L-300 en(pdf)
- Installation Manual Electrical Installation Lyovapor L-300 en(pdf)
- Pre-Installation Checklist Lyovapor™ L-300(pdf)
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Applications
From standard application to unlimited ice capacity
Biotechnology
Used in biotechnology development for drying biologically active products: Drying and stabilization of small quantities in micro titer plates or small flasks.
Chemical
For gentle and lossless drying in QC and R&D laboratories: Drying of most minute quantities in micro titer plates as well as small and large flasks or bulk drying is possible.
Education
For a wide range of applications in academic education: Complete temperature sensitive drying.
Environmental Analysis
Required for sample preparation and stabilization to monitor environmental pollution: During storage of samples in order to destroy micro-organisms. Drying, e.g. for SpeedExtractor.
Food and Natural Extracts
Used for developing function-al food and analytics: Solvent is removed during, drying without destroying, the natural substances such as proteins, minerals or vitamins.
Pharmaceutical
For various applications in QC as well as laboratory scale synthesis and formulation in R&D departments: Drying of peptides and proteins of amorphous and crystalline solutions.
