Encapsulator B-390 / B-395

For innovative microbeads and microcapsules

The versatile system for controlled encapsulation of active ingredients and materials for laboratory-scale research and development work. The simplicity and adaptability of the device allow its use in a variety of areas – pharmaceuticals, materials, cosmetics, the food industry and agriculture.

  • Capsule type:matrix beads or core shell capsules
  • Final particle size:150 μm - 4 mm
  • Productivity:1 - 40 mL / min
Encapsulator B-390 / B-395

Reliable

Improve the efficiency and reproducibility of your encapsulation process with the Encapsulator B-390 / B-395. Obtain more of a better quality product thanks to exceptionally tight particle size distributions and high yields.

User-friendly

The Encapsulator B-390 / B-395 offers you intuitive operation and easy maintenance so none of your time is wasted on mundane tasks. Since you can visualize the droplet formation process, you can also quickly and easily optimize your encapsulation process. With access to our broad application database and to our team of application specalists, you can operate the instrument perfectly adapted to your needs.

Versatile

Gain unmatched flexibility in encapsulation with a wide variety of options in how to use your Encapsulator B-390 / B-395. Choose between any particle diameter between 80 μm and 2000 μm. Use the encapsulator to produce monodisperse microbeads and microcapsules. Encapsulate microorganisms, organic and inorganic substances for more freedom in what and how you encapsulate.

Aseptic

The Encapsulator B-395 makes sterile encapsulation of cells, microorganisms and active ingredients possible. You can aseptically introduce and remove fluids and products to and from the reaction vessel. You can also readily integrate the encapsulation instrument in a GMP-compliant production process.

Increased efficiency

The low-impact encapsulation conditions made possible by the Encapsulator B-390 / B-395 can increase the efficiency and reproducibility of your encapsulation process. The encapsulation system offers you tight particle size distribution and high yields of a product with superior quality.

Flawless user experience

Enjoy a flawless user experience with the Encapsulator B-390 / B-395 thanks to intuitive operation and easy maintenace. The ability to directly see the droplet formation gives you comprehensive access to the process and enables you to quickly and confidently optimize your encapsulation. We offer extensive support, so you can easily adapt the system to your particular samples and needs. Rely on our established application database or talk to our certified application specialists to optimize and personalize your system performance.

Features

  • Nozzle system for production of large core-shell capsules (dia. 2 – 4 mm) by means of drop separation process

  • Concentric nozzle system for creating core-shell capsules (dia. 200 – 2000 μm)

  • Airflow-assisted nozzle system for producing beads (dia. 80 – 1000 μm) from highly viscous polymers

  • The integrated nozzle heater expands the breadth of applications. It enables the processing of melts such as wax or gelatine

  • Nozzle system with airstream dispersal and minimized dead space, tailor-made for low-impact encapsulation of cell agglomerates

  • The reaction vessel for the Encapsulator B-395 Pro is available with material certificates for GMP documentation

  • Easily calibrated syringe pump for low-loss feed of small sample quantities using sterile syringes of various volumes

Compare the Encapsulator B-390 / B-395

  • Encapsulator B-390

    B-390_comparison.tiff
    • Working mode:-
    • Nozzle heater for viscous samples:Yes
    • Minimum particle size:80 μm
    • Maximum partical size:2000 μm
    • Minimum sample throughput:0.5 mL/min
    • label missing:-
    • Vibration frequency:40 - 6000 Hz
  • Encapsulator B-395 Pro

    B-395_Pro_comparison.tiff
    • Working mode:-
    • Nozzle heater for viscous samples:-
    • Minimum particle size:80 μm
    • Maximum partical size:2000 μm
    • Minimum sample throughput:0.5 mL/min
    • label missing:-
    • Vibration frequency:40 - 6000 Hz
  • Encapsulator B-395 Pro GMP

    B-395_Pro_comparison.tiff
    • Working mode:-
    • Nozzle heater for viscous samples:-
    • Minimum particle size:80 μm
    • Maximum partical size:2000 μm
    • Minimum sample throughput:0.5 mL/min
    • label missing:-
    • Vibration frequency:40 - 6000 Hz
Thanks to the introduction of the new BUCHI Encapsulator, various micro-beads can be produced quickly, and the production of beads under sterile conditions is easy.Dr. Eunhye Lee - Utah-Inha DDS & Advanced Therapeutics Research, Korea

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Applications

Many different options for a wide range of industries

For more than 30 years BUCHI has been developing market leading solutions for laboratory spray drying and encapsulation. It is our utmost ambition to understand and meet your personal demands in particle formation technologies for the lab. Our reliable and tailored solutions for various industries include ingenious products, innovative systems and a highly professional application support.
  • Others

    Cell, bacteria and protein encapsulation, cell transplantation, biotransformation, cosmetics, fragrances, environmental applications

    Others
  • Academia

    For a wide range of applications in academic education: Full range of spray drying applications.

    Academia
  • Feed

    Encapsulation of additives, flavors, vitamins, proteins, probiotic bacteria, controlled release

    Feed
  • Food

    Encapsulation of additives, controlled release, nutraceuticals, functional foods, flavors, vitamins, proteins, probiotic bacteria, juice concentrate, milk powder

    Food
  • Materials and Nano technology

    Nanotechnology, catalysts, fuel cells, batteries, accumulators, ceramics, UV absorbers, pigments and coatings

    Materials and Nano technology
  • Pharmaceuticals

    Active pharmaceutical ingredients, drug delivery, vaccines, inhalable drugs, taste masking

    Pharmaceuticals