Sepbox 2D-2000

Automated separation of natural compounds

The Sepbox 2D-2000 sets new standards in purification accuracy and throughput. Its patented two-dimensional technology combines advanced HPLC and SPE for fast, automated compound isolation.

Detection:UV and ELSD
Pump:Prep HPLC mode
System Design:compact and fully automated

Automated operation reduces resources

Fully automated operation minimizes hands-on time and human error, making the Sepbox 2D-2000 highly scalable for high-throughput workflows. Its efficient design lowers costs and allows isolation of large compound libraries from complex natural sources with minimal manual effort.

Exceptional speed and throughput

The Sepbox 2D-2000 isolates up to 2,000 mg per run, separating a full extract in a single day and collecting up to 576 high-yield fractions automatically. It greatly accelerates natural product research and drug discovery workflows.

High purity with reproducible accuracy

The Sepbox 2D-2000 typically achieves over 90% recovery for polar and non-polar compounds, with up to 30% of fractions reaching 90–99% purity (ELSD). Standard UV detection with ELSD, enables reliable separation and detection across diverse extract types.