Spray Drying of Erythropoietin (EPO)
Spray Drying of Erythropoietin (EPO) with the Mini Spray Dryer B-290
Erythropoietin (EPO) is a glycoprotein hormone that plays a critical role in the regulation of red blood cell production. Spray drying is a widely used method for producing dry powders of EPO, which can be used in various pharmaceutical applications.
During the spray drying process, a liquid EPO solution is atomized into fine droplets and dried in a hot air stream to produce a dry powder. The resulting powder has good stability, solubility, and activity, making it ideal for use in various pharmaceutical applications.
Areas of spray drying of EPO include the selection of appropriate raw materials, formulation development, process optimization, and product characterization. The optimal processing conditions such as temperature, flow rate, and inlet/outlet conditions are determined to optimize the particle size, powder yield, and other physicochemical properties of the resulting powder.
Spray-dried EPO powders are commonly used in various pharmaceutical applications, such as the treatment of anemia in patients with chronic kidney disease, cancer, and other conditions. The use of spray drying technology ensures consistent quality and high production efficiency, making it a preferred method for producing dry powders of EPO.
Please see the application note No. 505 for starting parameters, formulations and some results.
