Aplikasi: Freeze Dryer

SpeedExtractor E-916, Syncore Analyst: Pressurized Solvent Extraction of a sludge sample for the determination of polycyclic aromatic hydrocarbons (PAHs)

The cell viabilities of microorganisms during storage are of economic importance for probiotic dietary food and feed supplements. By combining granulation and freeze drying, dust free particles homogeneous in size and composition can be obtained. This will enable a good particle flowability, an easier dosage and a faster reconstitution of the product can be obtained. Encapsulator as a granulator to prill the yeasts suspension into liquid nitrogen and form monodispersed beads that will then be freeze dried.

Freeze drying is a gentle form of drying and may be used to preserve foods without changing their appearance or taste. The freeze drying process includes the freezing of the food sample and subsequent applying a fine vacuum to the frozen sample. Under these conditions, the water in the food will sublimate, hence, the sample dries. In food applications, freeze drying is commonly used to make instant coffee and to dry and conserve fruits, vegetables or herbs.

In this Application Note sodium chloride (NaCl) and mannitol are used for freeze drying experiments. The unambiguous crystal structure of NaCl renders this salt a model compound. In contrast, mannitol is well known to crystallize in different polymorphs and it may form hydrates. Nevertheless, mannitol is the most used bulking agent for freeze dried pharmaceutical formulations. The benefits of using mannitol are that it crystallizes during freezing, creates a beautiful cake and permits drying processes at higher product temperatures, thus with higher sublimation rates compared to purely amorphous systems.

Truffles are products with limited shelf life and their sensory properties are rapidly lost. Hence, the expensive fungi become less valuable within a few days. Losses of volatile compounds, oxidation and enzymatic reactions are a considerable problem during their storage. Furthermore, the aroma profile is commonly modified as a result of elevated temperature processes or enzymatic reactions. Freeze drying the fungi avoids loss and degradation of volatile compounds due to the low temperatures applied during drying. The aromatic profile of truffles are maintained. Freeze dried truffles can either be rehydrated or directly used in dry form.

Penggunaan pelarut organik dalam alat pengering beku laboratorium

Freeze-dryers were initially intended to be used with water as a solvent. With new applications, freeze-drying is consequently being used more and more in combination with organic solvents instead of water. Organic solvents and inorganic acids and bases are often used in research and development prior to lyophilisation of the sample. The behavior of these new types of samples during freeze-drying must therefore be considered prior to the process.

Automatic freeze drying endpoint determination for vials application on Lyovapor™ L-300 Pro by pressure difference test, pressure rise test and temperature difference test

End point determination for a manifold set up in Lyovapor™ L-300 Pro by pressure difference test and pressure rise test

Lyovapor™ L-200: Freeze Drying of apples

We developed a freeze-drying method with optimized process time and residual moisture content for apples.

Lyovapor™ L-200: Freeze Drying of strawberries

We developed a freeze-drying method with optimized process time and residual moisture content for strawberries.

BUCHI Lyovapor™ L-250 Basic is applied in freeze drying active pharmaceutical compounds dissolved in organic solvent mixtures.

The pressure difference test in manifold drying chamber on Lyovapor™ is used to determine the end of the primary drying phase. A range of water-solvent mixtures is analyzed to identify conditions enabling reliable implementation for this test.

Pembimbing formulasi untuk sampel minyak kanabis

Dengan dokumen resmi gratis ini, dapatkan wawasan berguna mengenai pengeringan semprot dan enkapsulasi, dua teknik umum yang digunakan untuk memformulasi kanabinoid. Selain itu, pelajari tentang alasan kita memerlukan kanabinoid dalam bentuk serbuk. 

Gunakan panduan ini untuk mudah mendapatkan bentuk kanabinoid yang dapat dijual.  

Waktu freeze drying Anda tetap yang terdepan! – Poster

Tempelkan poster liofilisasi di dinding Anda. Unduh poster secara gratis sekarang – "Waktu freeze drying Anda tetap yang terdepan!"

Pembimbing Pengeringan Beku Vol. 1: Teori dasar dan penerapanPanduan ini memberi Anda pengetahuan dasar dan penerapan untuk Pengeringan Beku.

Panduan ini memberi Anda pengetahuan dasar dan penerapan untuk Pengeringan Beku.

Pembimbing Pengeringan Beku Vol. 2: Toolkit bergambar untuk pengguna umum

Panduan ini memberi Anda pengetahuan tentang perangkat keras, proses pengeringan beku, ikhtisar parameter yang paling penting dan langkah-langkah dalam preparasi sampel.