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The use of organic solvents in laboratory freeze-dryer

Freeze-dryers were initially intended to be used with water as a solvent. With new applications arising, products that are not soluble in water are increasingly present in chemistry applications. Consequently, freeze-drying is being used more and more in combination with organic solvents instead of water.
Organic solvents and inorganic acids and bases are often used in research and development prior to lyophilisation of the sample. The behavior of these new types of samples during freeze-drying must therefore be considered prior to the process.