With the Mini Spray Dryer B-290 or with the Nano Spray Dryer B-90 with the Inert Loop B-295 it is possible to spray with organic solvents without risk of explosion, because the system works under inert conditions.
The outlet temperature is depending on the parameters inlet temperature, sample feed rate, sample concentration and aspirator rate. A change in one of those parameters will either cause the outlet temperature increase or decrease.
The limiting factor is the peristaltic pump. So the sample still has to be pumpable. This will be possible with a viscosity up to 300 cps with the Mini Spray Dryer B-290 or 10 cps with the Nano Spray Dryer B-90.
Major differences: B-90 for smaller sample quantities (mL samples, mg powder amounts), higher yields up to 90% and smaller particle sizes (submicron)
B-290 is the classical spray dryer for medium laboratory sample quantities at a wide range of applications (also viscous substances and fruit juices possible). Its scale-up is more straigthforward.