Generate added value
Encapsulation is the immobilization of active ingredients in a matrix or a core-shell capsule which can range from a few hundred nano-meters up to a several millimeters in size. The matrix or shell is used as a retention network and a protection shield for the active ingredient as well as a barrier through which only specific compounds can diffuse.
The six main benefits for encapsulation a material:
- Protection from conditions such as heat, moisture, oxygen and will prolong shelf-life
- Controlled or sustained release to help develop new deliver mechanisms
- Targeting to specific sites direct delivery to the site where it is required.
- To enable the encapsulated material to act as extraction aides for product removal.
- Improved flow properties by converting a liquid into a solid particle which improves handling, usage and storage.
- Improved organoleptic properties to mask its unpleasant taste and/or small and improve its visual appearance as well as its texture.
These benefits can give your product added value for application in several industries such pharmaceutical, medical & biotech, chemical, agricultural, food & feed, personal care products, cosmetics, etc.
BUCHI offers you two main encapsulation technologies for you to create innovative products in your daily R&D work. These technologies allow you to create a wide range of particle types (wet, dry, powders, beads and capsules) and particle sizes (from nano- to millimeter scale).
|Spray Drying||Prilling by vibration|
|Particles type||Dry homogenous or matrix particles||Liquid core beads or capsules (wet) (possible to dry after)|
(= shell material)
|Sugars, starch, cellulose, gum, polymers, wax, proteins (or no excipients)||Polymers, alginate, gelatin, wax, gum, proteins, cellulose, whey|
∙Short process time
∙Low cost at industrial scale
∙Protection of core material
∙Particle hardening in cooling or polymerization bath
∙Short process time
|Process conditions||Mild drying conditions||Extremely gentle|
|Particle size distribution||Broad||Narrow|
|Particles size||Controllable particle size and morphology
(0.3 – 60 μm)
|Selectable particle size
(100 – 2000 μm)